A robust representation of hydrogeological properties of the examined study area in discretization step is essential in groundwater modelling to improve the accuracy and efficiency of the model. A number of studies have investigated the effect of grid cell size in model discretization using comparison of performances of different models representing different cell sizes. However, although grid size refinement effect on model performances was calculated, the impact of mean slope was not conclusively discussed. In this study, five models distinguished by five spatial discretization schemes; 10 x 10 m, 20 x 20 m, 30 x 30 m, 40 x 40 m and 50 x 50 m were constructed. Using PEST, hydraulic conductivity and specific yield values over a selection of pilot points were estimated. The effect of surface slope is discussed in order to recommend the most appropriate location for observation well placement in terms of topographical characteristic. It is confirmed that the deterioration of model performance is controlled by mean slope of the surface. Results reveal that model performance increases substantially for areas of low slope (< 3 %) and medium slope (3 ∼ 10 %) for smaller a grid cell size. Therefore, to improve model performance, it is recommended that the observations wells are placed in areas of low and medium slopes.