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Interpreting atomic force microscopy measurements of hydrodynamic and surface forces with nonlinear parametric estimation

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conference contribution
posted on 2024-07-09, 14:48 authored by Song Cui, Rogerio Manica, Rico F. Tabor, Derek Chan
A nonlinear parameter estimation method has been developed to extract the separation-dependent surface force and cantilever spring constant from atomic force microscope data taken at different speeds for the interaction between a silica colloidal probe and plate in aqueous solution. The distinguishing feature of this approach is that it exploits information from the velocity dependence of the force-displacement data due to hydrodynamic interaction to provide an unbiased estimate of the functional form of the separation-dependent surface force. An assumed function for the surface force with unknown parameters is not required. In addition, the analysis also yields a consistent estimate of the in situ cantilever spring constant. In combination with data from static force measurements, this approach can further be used to quantify the extent of hydrodynamic slip.

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PDF (Published version)

ISSN

0034-6748

Conference name

Review of Scientific Instruments

Volume

83

Issue

10

Publisher

American Institute of Physics

Copyright statement

Copyright © 2012 American Institute of Physics. The published version is reproduced with the permission of the publisher.

Language

eng

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