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Black silicon as a platform for bacterial detection

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posted on 2024-07-26, 13:58 authored by Jennifer S. Hartley, M. Myintzu Hlaing, Gediminas Seniutinas, Saulius JuodkazisSaulius Juodkazis, Paul StoddartPaul Stoddart
Surface-enhanced Raman scattering (SERS) shows promise for identifying single bacteria, but the short range nature of the effect makes it most sensitive to the cell membrane, which provides limited information for species-level identification. Here, we show that a substrate based on black silicon can be used to impale bacteria on nanoscale SERS-active spikes, thereby producing spectra that convey information about the internal composition of the bacterial capsule. This approach holds great potential for the development of microfluidic devices for the removal and identification of single bacteria in important clinical diagnostics and environmental monitoring applications.

Funding

Photonic crystals at visible wavelengths

Australian Research Council

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ARC Training Centre in Biodevices

Australian Research Council

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History

Available versions

PDF (Published version)

ISSN

1932-1058

Journal title

Biomicrofluidics

Volume

9

Issue

6

Article number

article no. 61101

Pagination

6 pp

Publisher

American Institute of Physics

Copyright statement

Copyright © 2015 AIP Publishing LLC. The published version of the article is reproduced with permission of the publisher. It may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Applied Physics Letters and may be found at http://dx.doi.org/10.1063/1.4934966

Language

eng

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