Reduced effects of spherical aberration on penetration depth under two-photon excitation
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posted on 2024-07-09, 23:45 authored by Djenan Ganic, Xiaosong Gan, Min GuWe compare the effects of spherical aberration on the penetration depth of single-photon and two-photon excitation for instances in which the aberration is caused by the refractive-index mismatch when a beam is focused through an interface. It is shown both theoretically and experimentally that two-photon fluorescence imaging experiences less spherical aberration and can thus propagate to a deeper depth within a thick medium.
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2155-3165Journal title
Applied OpticsVolume
39Issue
22Pagination
2 ppPublisher
Optical Society of AmericaCopyright statement
Copyright © 2000 Optical Society of America. The published version is reproduced in accordance with the copyright policy of the publisher. This paper was published in Applied Optics and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=ao-39-22-3945. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.Language
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