A lymphocyte homing algorithm

T-lymphocytes are imprinted with chemical information of the general tissue that is exposed to pathogen. T-cells express specific receptors for this chemical signature and preferentially traffic from the recirculation pathway to the infected tissue. This effect is referred to as lymphocyte homing and provides a targeted response to pathogenic invasion. This work proposes a minimal recirculating clonal selection algorithm that is specialised such that lymphocytes preferentially home to tissue locations (nodes in a directed cyclic graph) where they are anticipated to be most useful.