posted on 2024-07-11, 19:55authored byJason Brownlee
The clonal selection principle describes the selection and maturation of lymphocytes, accounting for the diversity of the antibodies they produce and the tolerance they have to selfantigens. The theory does not exist in isolation, the receptors, the host, and the antigens have a context that is commonly ignored when this principle is realised as a computational intelligence algorithm. This work attempts to provide context to the principle by introducing a spatial structure in which to house membrane bound receptors, and which simple clonal selection operations (as previously defined for the elaborated clonal selection algorithm) are applied.