The physiology of lymphocyte migration

White blood cells (lymphocytes) are the mobile cells that make up the recognition and response component of the acquired immune system. There are pools of lymphocytes that recirculate the blood stream and the lymphatic system, there are lymphocytes that selectively home to tissues close to where the cells were created, and there are pools lymphocytes that are recruited to sites of infection and inflammation. The lymphoid tissue of the lymphatic system provides the structural scaffold for the mobility of these cells, although interestingly the migratory behaviour is controlled at the finest level -- by localised chemicals and receptors on the cells themselves. This work summarises the mobility of lymphocytes providing perspectives of cell movements from the lymphatic system, movement types, cell types, and cell classes. It is believed that this review and further more detailed studies of specific aspects of cell mobility may provide a fertile basis for the design of distributed information and computation models.