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Cerebrovascular reactivity, metabolism and cognitive function in healthy aging

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posted on 2024-07-12, 19:00 authored by Sarah Catchlove
This thesis investigated the impact of brain blood vessel integrity, cerebral oxygen consumption and blood flow on cognitive performance in normally aging adults. The research was conducted using various neuroimaging applications to measure different aspects of vascular function. The novel findings enhance scientific knowledge of the contribution of hemodynamic markers to memory and attention tasks. Specifically, in older adults, the reactivity of small capillaries in the hippocampus were found to contribute to memory function, and blood flow was inversely related to attention task performance.

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Thesis type

  • Thesis (PhD by publication)

Thesis note

Thesis by publication, submitted for the Degree of Doctor of Philosophy, Swinburne University of Technology, 2019.

Copyright statement

Copyright © 2019 Sarah Catchlove.

Supervisors

Andrew Pipingas

Language

eng

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