posted on 2024-07-12, 20:52authored byAlexander Dart
The rising threat of antibiotic resistance is placing increasing urgency on developing new materials and technologies to dynamically combat resistant infections, particularly for immediate wound care. The research described in this Thesis demonstrates different loading strategies of antimicrobial and antiviral agents into electrospun fibres. Loaded fibres are assessed for their release profiles of active agents, and subsequently the effectiveness on the inhibition of pathogens and the biocompatibility of the fibres in mammalian cell culture. Improved drug delivery of biologically active agents has direct benefits for wound treatment and healthcare medications.
History
Thesis type
Thesis (PhD)
Thesis note
A thesis submitted for the degree of Doctor of Philosophy, Swinburne University of Technology, 2022.