Development of RAFT derived polymer coatings to prevent medical device related infections

The use of medical devices can be associated with serious clinical complications due to device-related infections. Over the past few decades, the chemical modification of device surfaces with thin polymeric coatings has been demonstrated to be a promising strategy to prevent these infections. This project developed multifunctional antibacterial coatings featuring low surface adherence against Escherichia coli and Staphylococcus aureus as well as the release of antibacterial agencies such as antibiotics to inhibit the proliferation of planktonic bacteria both on the surface and in the vicinity of the coatings. This approach is expected to be translated into biomedical device applications.