Investigation of a framework for epidemiological studies of Campylobacter jejuni based on the combination of genetic markers and MALDI-TOF MS typing schemes

Campylobacter jejuni is the most common foodborne bacterial pathogen responsible for a significant burden to public health worldwide. Bacterial typing schemes play an important role in the control of foodborne infections by helping source tracing and revealing the routes of transmission of pathogens. This study investigated the suitability of combinations of genetic markers based typing schemes and Matrix assisted laser desorption/ Ionization- time of flight mass spectrometry. The application of the developed framework addressed the need for more rapid, cost effective and accurate methodological approach to identify the origin and thus control C. jejuni infections.