Investigation of the biointerfaces of nanostructured surfaces

Generating materials with nano-structured surfaces has been a focus of research in the last few years, especially for biomedical applications due to their unique physical, chemical and biological properties. A number of nanostructured materials has been introduced, however the multidimensional cell activities that taking place at the surface biointerfaces require more in-depth understandings for their successful applications. The findings included in this PhD thesis contribute to the body of knowledge on how pathogenic bacteria and mammalian cells specifically response to different types of surface nanostructures, offering a prospect of success in designing long-term antibacterial, biocompatible materials.