Isolation, Characterisation and function of Extracellular Vesicles derived from Mesenchymal Stem Cells

Stem cells have been used as ideal candidates for tissue regeneration to cure many diseases in the last three decades. As all the cells, stem cells release nanoparticles known as extracellular vesicles. Extracellular vesicles contain proteins, lipids and RNAs, play important biological roles in cell-to-cell communication. Extracellular vesicles may play an important role in stem cell therapeutic efficacy. In this thesis, we focus on isolation, characterisation and function of extracellular vesicles derived from stem cells. Our finding have explored potential benefits of extracellular vesicles. In the future, extracellular vesicles derived from stem cells may become an “off-the-shelf" cell-free medicine.