Rohan’s thesis focussed on the development of a novel microwave-assisted procedure to prepare lipid-based colloidal drug carriers called solid lipid nanoparticles (SLNs). SLNs are an attractive alternative to traditional drug carriers due to the use of biocompatible lipid materials, their solid nature, nanometre size and drug release properties. An array of drugs was encapsulated using this innovative technique and their characterization, cellular uptake, drug release behaviour and stability were investigated. Upon development this method would facilitate fabrication of SLNs for use as potential drug carriers.
History
Thesis type
Thesis (PhD)
Thesis note
Thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy, Swinburne University of Technology, 2016.