New approaches in the fabrication of multi-dimensional smart materials for biotechnological applications

This thesis has been primarily devoted to the investigation of three types of newly fabricated multi-dimentional bio-inspired material surfaces. These materials were: commerical purity Grade 2 titanium, black silicon and a three-dimensional poly (vinyl alcohol) (PVA) - Vinyl Pyrrolidone (VP) hydrogel. The biomimetric and antibacterial titanium and black silicon surfaces produced in this study were shown to possess selective bactericidal activity, and the ability to enhance the attachment and proliferation of primary human fibroblasts. These smart nano-structured surfaces have excellent prospects for biomedical applications.