Optical and Electrical Costimulation of Optogenetically-modified Neurons

This study investigated new approaches to controlling brain cells for bionic devices such as the cochlear implant. These devices typically use electrical signals to connect with and control brain cells. In this study, cells were genetically modified so that they could be controlled by light (a technique known as optogenetics). A combination of light and electrical stimulation was shown to interact to improve the response of brain cells compared to either light or electrical stimulation on its own. These results may improve future bionic devices which help people regain lost functions like movement, sight or hearing.