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Quorum quenching processes through surface treatments

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posted on 2024-07-13, 08:56 authored by Sanjida Halim Topa
Certain bacteria associated with humans use chemical communication mechanisms to switch on their pathogenic characteristics leading to chronic infections. Antibiotics function by killing pathogenic bacteria but bacteria frequently develop resistance. Dr Topa’s research used a component of cinnamon oil that interfered with the pathogen’s chemical communication mechanisms, thus precluding pathogenesis development. This approach limits the tendency for bacteria to develop resistance since the bacteria are not killed. The cinnamon oil component was fabricated into novel nanofibre materials, which demonstrated anti-pathogenesis action in a non-killing fashion. The projected practical outcomes include solutions to medical implant device and chronic wound infections.

History

Thesis type

  • Thesis (PhD)

Thesis note

The thesis is submitted for the degree of Doctor of Philosophy, Swinburne University of Technology, 2018.

Copyright statement

Copyright © 2018 Sanjida Halim Topa.

Supervisors

Linda Louise Blackall

Language

eng

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