Syzygium Polyanthum (Wight) from Sarawak as a potential source of compounds exhibiting in vitro anti-cancer activity against nasopharyngeal carcinoma (NPC)

Nasopharyngeal carcinoma is a cancer of the nasopharynx. The Malaysian state of Sarawak reports one of the highest incidence rates globally, coming in close to front runners Hong Kong and China. Natural products have garnered research interest for drug discovery, depicted by Aspirin, Morphine and Taxol, all derived from natural plant sources. Sarawak evokes images of dense forests rich in biodiversity, presenting the perfect canvas for bioprospecting. This thesis focuses on Syzygium Polyanthum (Wight) plant from Sarawak exhibiting activity against nasopharyngeal carcinoma cells. Computational-learning platforms were employed and validated by molecular methods to identify the anti-nasopharyngeal cancer mechanisms of the plant.